Company Profile

PAT^®️ Technology (Peripheral Arterial Tone)

PAT®️ technology is a non-invasive window to the cardiovascular system and autonomic nervous system. Peripheral Arterial Tone (PAT®️) signal is a proprietary technology used for non-invasively measuring arterial tone changes in peripheral arterial beds.

ThePAT®️ signal is measured from the fingertip by recording finger arterial pulsatile volume changes.
Based on PAT®️ technology, the non-invasive EndoPAT system comprises a measurement apparatus that supports a pair of modified plethysmographic bio-sensors. The unique feature of the PAT®️ bio-sensors is that they impart a uniform sub-diastolic pressure field to the distal two-thirds of the fingers including their tips. Applying the pressure in this way is extremely important as it:

• Prevents distal venous blood pooling, that can induce a veno-arteriolar vasoconstriction reflex
• Unloads arterial wall tension which generates a greater dynamic range of the measured PAT®️ signal
• Fixates thePAT®️ bio-sensor to the finger, which reduces movement artifacts

Risk Score Calculator

The EndoPAT®️ Risk Score Calculator provides the 3 most commonly used cardiovascular risk assessment methods:

• Framingham Risk Score: Estimates 10 year risk of Coronary Heart Disease, MI or cardiac death (Adults treatment panel III, JAMA 2001). Applies to subjects without known heart disease or diabetes. Utilities different models for men and women using the following predictors: age, total cholesterol, HDL, systolic blood pressure, treatment for hypertension and smoking.
• Score: The European estimate of a 10 year risk of fatal CVD (EHJ, 2003). Charts are divided to low-risk regions (Belgium, France, Greece, Italy, Luxemburg, Spain and Portugal) and high-risk regions (all other European countries) using the following predictors: gender, age, total cholesterol, systolic blood pressure, and smoking.
• Reynolds Risk Score: Provides 10 years’ risk of MI, stroke, revascularization or cardiac death (JAMA 2007, Circ 2008). Reynolds risk score uses the following predictors: gender, age, total cholesterol, HDL, systolic blood pressure, hsCRP, and parent MI before age 60.